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Comparative Evaluation of Physicochemical Properties of Some Commercially Available Brands of Metformin Hcl Tablets in Lagos, Nigeria

There are several generics of metformin hydrochloride tablets available within the drug delivery system globally. Availability of numerous brands of Metformin tablets in Nigerian drug market today places health practitioners in a dilemma of generic substitution. The objective of the study was to determine the biopharmaceutical and chemical equivalence of eight brands of Metformin tablets marketed in Nigeria using in vitro tests. The physicochemical equivalence of eight brands of Metformin hydrochloride tablets were assessed through the evaluation of both official and non-official standards suc…

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