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Climate, β-lactam stability, and antimicrobial resistance in Nigeria: a review protocol
Title: Climate, β-lactam stability, and antimicrobial resistance in Nigeria: a review protocol Research question: Does the available evidence support a demonstrated causal chain from tropical climate/storage exposure, through β-lactam chemical degradation, to reduced antimicrobial exposure, altered pharmacokinetic/pharmacodynamic target attainment, and resistance selection in Nigeria — or only individually plausible components of that chain? Eligibility criteria: Population/setting: Nigerian clinical, environmental, or pharmaceutical-quality studies as primary evidence; non-Nigerian studies el…
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